Transitions for Regulating Early Transcription
نویسندگان
چکیده
Gene expression is largely regulated during the initiation of RNA polymerase II (PolII) transcription. In this issue, Kouzine et al. show that control of DNA melting is one of the critical rate-limiting steps for productive mRNA elongation. We discuss these findings in the context of other key energetic transitions.
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عنوان ژورنال:
- Cell
دوره 153 شماره
صفحات -
تاریخ انتشار 2013